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Article

Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype.

Cancer research - 15 Mar 2008

Kumar Binod, Koul Sweaty, Khandrika Lakshmipathi, Meacham Randall B, Koul Hari K

Abstract excerpt

Reactive oxygen species (ROS) and the coupled oxidative stress have been associated with tumor formation. Several studies suggested that ROS can act as secondary messengers and control various signaling cascades. In the present studies, we characterized the oxidative stress status in three different prostate cancer cells (PC3, DU145, and LNCaP) exhibiting various degree of aggressiveness and normal prostate cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18339858
DOI: 10.1158/0008-5472.CAN-07-5259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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