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Article

A differential response of wild type and mutant promoters to TFIIIB70 overexpression in vivo and in vitro.

Nucleic acids research - 15 May 1998

Sethy-Coraci I, Moir R D, López-de-León A, Willis I M

Abstract excerpt

TFIIIB, the initiation factor for transcription by RNA polymerase III (pol III) is, in yeast, composed of three subunits: TBP, TFIIIB70/Brf1 and TFIIIB90. To determine the extent to which each of these subunits is limiting for pol III transcription, the effect of overexpressing each subunit was assessed on the expression of wild-type and promoter mutant pol III genes both in vivo and in vitro . In vivo , we find...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 9580684
DOI: 10.1093/nar/26.10.2344
PMCID: PMC147558

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A differential response of wild type and mutant promoters to TFIIIB70 overexpression in vivo and in vitro.PMID 9580684Read ↗

Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes.Semantic proximity Read ↗

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TFIIA has activator-dependent and core promoter functions in vivo.Semantic proximity Read ↗

Mutational analysis of yeast TFIIB. A functional relationship between Ssu72 and Sub1/Tsp1 defined by allele-specific interactions with TFIIB.Semantic proximity Read ↗

Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.Semantic proximity Read ↗

A mutation in the second largest subunit of TFIIIC increases a rate-limiting step in transcription by RNA polymerase III.Semantic proximity Read ↗

A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB.Semantic proximity Read ↗

Assembly of transcription factor IIB at a promoter in vivo requires contact with RNA polymerase II.Semantic proximity Read ↗

Functional interchangeability of TFIIIB components from yeast and human cells in vitro.Semantic proximity Read ↗

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae.Semantic proximity Read ↗

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