Article
Functional interchangeability of TFIIIB components from yeast and human cells in vitro.
The EMBO journal - 1 Aug 1997
Teichmann M, Dieci G, Huet J, Rüth J, Sentenac A, Seifart K H
Abstract excerpt
In eukaryotes, TFIIIB is required for proper initiation by RNA polymerase III. In the yeast Saccharomyces cerevisiae a single form of TFIIIB (gammaTFIIIB) is sufficient for transcription of all pol III genes, whereas in extracts derived from human cells two different hTFIIIB complexes exist which we have previously designated as hTFIIIB-alpha and hTFIIIB-beta. Human TFIIIB-alpha is a TBP-free entity and must be...
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