Article
The PCF1-1 mutation increases the activity of the transcription factor (TF) IIIB fraction from Saccharomyces cerevisiae.
Nucleic acids research - 25 Jul 1992
Willis I, Oksman A, López-De-León A
Abstract excerpt
PCF1-1 is a dominant suppressor of a tRNA gene A block promoter mutation (A19) in Saccharomyces cerevisiae. Transcriptional activation by PCF1-1 was examined in vitro using whole-cell extracts and purified factors derived from mutant and wild-type strains. These experiments show that PCF1 is a ge...
Topics
- Base Sequence
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Suppressor
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- RNA Polymerase III
- RNA, Transfer
- Saccharomyces cerevisiae
- Transcription Factor TFIIIB
- Transcription Factors
- Transcription Factors, TFIII
- Transcription, Genetic
- Transcription Factor TFIIIC