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Article

A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB.

The EMBO journal - 15 Apr 1996

Rüth J, Conesa C, Dieci G, Lefebvre O, Düsterhöft A, Ottonello S, Sentenac A

Abstract excerpt

Class III genes depend on TFIIIB for recruitment of RNA polymerase III. Yeast TFIIIB is comprised of three components: TBP, TFIIIB70 and a 90 kDa polypeptide contained in the fraction B". We report the isolation of the yeast gene TFC7 which, based on genetic and biochemical evidence, encodes the 90 kDa polypeptide. TFC7 was isolated as a multicopy suppressor of temperature-sensitive mutations in the two largest...

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Source

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Identifiers

PMID: 8617241
PMCID: PMC450113

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB.PMID 8617241Read ↗

Multiple roles of the tau131 subunit of yeast transcription factor IIIC (TFIIIC) in TFIIIB assembly.Semantic proximity Read ↗

Interaction between yeast RNA polymerase III and transcription factor TFIIIC via ABC10alpha and tau131 subunits.Semantic proximity Read ↗

Complex interactions between yeast TFIIIB and TFIIIC.Semantic proximity Read ↗

Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae.Semantic proximity Read ↗

A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70.Semantic proximity Read ↗

A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration.Semantic proximity Read ↗

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae.Semantic proximity Read ↗

Characterisation of fission yeast alp11 mutants defines three functional domains within tubulin-folding cofactor B.Semantic proximity Read ↗

Two components of Saccharomyces cerevisiae transcription factor IIIB (TFIIIB) are stereospecifically located upstream of a tRNA gene and interact with the second-largest subunit of TFIIIC.Semantic proximity Read ↗

A mutation in the C31 subunit of Saccharomyces cerevisiae RNA polymerase III affects transcription initiation.Semantic proximity Read ↗

A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIB-related factor TFIIIB70.Semantic proximity Read ↗

TFIIB/SUA7(E202G) is an allele-specific suppressor of TBP1(E186D).Semantic proximity Read ↗

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