Article
A novel upstream RNA polymerase III promoter element becomes essential when the chromatin structure of the yeast U6 RNA gene is altered.
Molecular and cellular biology - 1 Oct 2001
Martin M P, Gerlach V L, Brow D A
Abstract excerpt
The Saccharomyces cerevisiae U6 RNA gene, SNR6, possesses upstream sequences that allow productive binding in vitro of the RNA polymerase III (Pol III) transcription initiation factor IIIB (TFIIIB) in the absence of TFIIIC or other assembly factors. TFIIIC-independent transcription of SNR6 in vitro is highly sensitive to point mutations in a consensus TATA box at position -30. In contrast, the TATA box is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.