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Article

The effect of a nested set of C-terminal substituted deletions on the function of the alpha subunit of Escherichia coli RNA polymerase.

The international journal of biochemistry & cell biology - 1 Dec 1997

Thomas M S, Zou C, Ishihama A, Glass R E

Abstract excerpt

A genetic screen was devised to obtain plasmid-borne rpoA alleles exhibiting partial or no complementation of the chromosomal Escherichia coli rpoA341 allele responsible for a pleiotropic phenotype. Nine of the ten mutants obtained carried single base pair deletions within the 3' end of rpoA resulting in frameshifting into a 72 codon +1 orf extending from within codon L262 and terminating 16 bp downstream of the...

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PMID: 9570142
DOI: 10.1016/s1357-2725(97)00091-5

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