Article
Isolation, purification, and in vitro characterization of recessive-lethal-mutant RNA polymerases from Escherichia coli.
Journal of bacteriology - 1 Sept 1996
Tavormina P L, Landick R, Gross C A
Abstract excerpt
The beta subunit of prokaryotic RNA polymerase shares significant sequence similarity with its eukaryotic and archaeal counterparts across most of the protein. Nine segments of particularly high similarity have been identified and are termed segments A through I. We have isolated severely defecti...
Topics
- Amino Acid Sequence
- Animals
- Chromosome Mapping
- DNA-Directed RNA Polymerases
- Escherichia coli
- Genes, Lethal
- Genes, Recessive
- Molecular Sequence Data
- Mutation
- Peptide Chain Elongation, Translational
- Phenotype
- Sequence Homology, Amino Acid