Article
An RNA polymerase alpha subunit mutant impairs N-dependent transcriptional antitermination in Escherichia coli.
Molecular microbiology - 1 Jan 1997
Obuchowski M, Wegrzyn A, Szalewska-Pałasz A, Thomas M S, Wegrzyn G
Abstract excerpt
We show that the rpoA341 mutation in the gene encoding the alpha subunit of Escherichia coli RNA polymerase results in a decreased level of transcripts originating from the lytic promoters PL and PR of infecting lambda phage. However, using lacZ fusions we demonstrate that initiation of transcription from both PL and PR is not impaired in the rpoA341 host. Rather, it is the level of the longer, antiterminated PL-...
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