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Article

Cytochrome P4502E1 inducibility and hydroxyethyl radical formation among alcoholics.

Journal of hepatology - 1 Apr 1998

Dupont I, Lucas D, Clot P, Ménez C, Albano E

Abstract excerpt

BACKGROUND/AIMS: Animal studies have shown that the induction of cytochrome P4502E1 (CYP2E1) modulates oxidative damage induced by ethanol. Since CYP2E1 activity varies substantially in humans, we have investigated whether differences in CYP2E1 activity might influence the formation of hydroxyethyl free radicals and the stimulation of lipid peroxidation among alcohol abusers. METHODS: Chlorzoxazone oxidation, an...

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Source

Identifiers

PMID: 9566824
DOI: 10.1016/s0168-8278(98)80279-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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