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Article

Cytochrome P4502E1 phenotyping by the measurement of the chlorzoxazone metabolic ratio: assessment of its usefulness in workers exposed to styrene.

International archives of occupational and environmental health - 1 Sept 2002

Haufroid Vincent, Buchet Jean-Pierre, Gardinal Sophie, Lison Dominique

Abstract excerpt

OBJECTIVES: To analyse the relationship between cytochrome P4502E1 (CYP2E1) activity as assessed by the chlorzoxazone metabolic ratio (CMR) and frequent CYP2E1 genotypes ( CYP2E1*5B, *6, *1B and *1D) and to assess the value of CMR in refining the biomonitoring of exposure to styrene. METHODS: Thirty-one workers from a fibreglass-reinforced plastics factory took part in the study. Ambient styrene concentration was...

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PMID: 12172891
DOI: 10.1007/s00420-002-0334-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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