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Article

A microplate allele-specific oligonucleotide hybridization assay for detection of factor V Leiden.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 1997

Zehnder J L, Benson R C, Cheng S

Abstract excerpt

Factor V Leiden is the most common genetic risk factor for thrombosis. Currently, the determination of factor V Leiden genotype is limited to laboratories with expertise in molecular methods to develop "home brew" assays using polymerase chain reaction (PCR) to amplify genomic DNA, followed by analysis of Mnl I restriction fragments. These methods are not standardized, are labor intensive, and have low...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9559295
DOI: 10.1097/00019606-199712000-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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