Article
Multiple sample amplification and genotyping integrated on a single electronic microarray.
Electrophoresis - 1 Oct 2004
Huang Ying, Shirajian Jack, Schroder Astrid, Yao Zuxu, Summers Tamara, Hodko Dalibor, Sosnowski Ron
Abstract excerpt
We report a novel method that allows simultaneous in situ amplification and then genotyping of single nucleotide polymorphism (SNP) for multiple samples on a single electronic microarray. The locus coding for one of the common inherited thrombosis risk factors, Factor V Leiden (FVL), was chosen as a model system for SNP analysis. This method combines strand displacement amplification (SDA) with electrophoretic...
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