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Genotyping of mutations in the beta-globin gene using allele specific hybridization.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Poulsen Lena, Petersen Jesper, Dufva Martin

Abstract excerpt

The use of DNA microarrays for genotyping is economically favorable when compared to real-time PCR and DNA sequencing. Here, we demonstrate a DNA microarray-based assay using allele-specific oligonucleotide (ASO) probes for genotyping mutations in the beta-globin gene. The assay makes use of agarose film coated glass slides as substrate, unmodified melting temperature matched ASO probes, target amplification and...

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PMID: 19381980
DOI: 10.1007/978-1-59745-538-1_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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