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Article

Mouse CD1-Autoreactive T Cells Have Diverse Patterns of Reactivity to CD1+ Targets

1 Apr 1998

Abstract excerpt

Humans and mice contain significant populations of T cells that are reactive for autologous CD1 molecules. Using a panel of five mouse CD1 (mCD1)-autoreactive T cell hybridomas, we show here that this autoreactivity does not correlate with the level of CD1 expression. In some cases, these autoreactive T cells can distinguish between different cell types that express the same CD1 molecule, suggesting that some...

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PMID: 9558068
DOI: 10.4049/jimmunol.160.8.3681

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