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Article

A single amino acid defines cross-species reactivity of tree shrew (Tupaia belangeri) CD1d to human invariant natural killer T (iNKT) cells.

Immunology - 1 Dec 2009

Zhang Ping, Li Demin, Stewart-Jones Guillaume, Shao Xiaoli, Zhang Yuanxu, Chen Qiongyu, Li Yijiang, He You-Wen, Xu Xiao-Ning, Zhang Hua-Tang

Abstract excerpt

The non-classical major histocompatibility complex (MHC) class I molecule CD1d presents lipid antigens to invariant natural killer T (iNKT) cells, which are an important part of the innate immune system. CD1d/iNKT systems are highly conserved in evolution, and cross-species reactivity has been suggested to be a common feature of different animals based on research in humans and mice. However, we found that CD1d...

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Share to Antigen Presentation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19863613
DOI: 10.1111/j.1365-2567.2009.03133.x
PMCID: PMC2792134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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