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Article

Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity.

Journal of virology - 1 May 1998

Barco A, Carrasco L

Abstract excerpt

The expression of poliovirus 2BC protein in yeast and mammalian cells leads to a number of metabolic and morphological alterations, such as growth inhibition, intracellular membrane proliferation, blockade of the exocytic pathway, and enhanced membrane permeability. Yeast cells that express poliovirus 2BC in an inducible manner were used to identify the regions of 2BC implicated in the modifications of these...

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Identifiers

PMID: 9557636
DOI: 10.1128/JVI.72.5.3560-3570.1998
PMCID: PMC109576

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