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Article

Truncation of herpes simplex virus type 2 glycoprotein B increases its cell surface expression and activity in cell-cell fusion, but these properties are unrelated.

Journal of virology - 1 Sept 2002

Fan Zhenghong, Grantham Michael L, Smith M Shane, Anderson Eric S, Cardelli James A, Muggeridge Martin I

Abstract excerpt

Formation of small polykaryons by cell-cell fusion is characteristic of herpes simplex virus (HSV) lesions, but the great majority of viruses isolated from such lesions produce only limited cell fusion in tissue culture. Because of this, HSV laboratory strains that produce extensive cell fusion (syncytium formation) in culture are regarded as variants or mutants. Furthermore, the rarity of clinical isolates able...

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Identifiers

PMID: 12186911
DOI: 10.1128/jvi.76.18.9271-9283.2002
PMCID: PMC136473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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