Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retrovirus-mediated DNA repair gene transfer into xeroderma pigmentosum cells: perspectives for a gene therapy.

Cell biology and toxicology - 1 Mar 1998

Zeng L, Sarasin A, Mezzina M

Abstract excerpt

The rare hereditary disease xeroderma pigmentosum (XP) is clinically characterized by extreme sun sensitivity and an increased predisposition for developing skin cancer. Cultured cells from XP patients exhibit hypersensitivity to ultraviolet (UV) radiation due to the defect in nucleotide excision repair (NER), and other cellular abnormalities. Seven genes identified in the classical XP forms, XPA to XPG, are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Vectors
Share to Cell Survival
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA Repair

Share to Fibroblasts

Share to Phenotype

Source

Identifiers

PMID: 9553721
DOI: 10.1023/a:1007477820594

Genes

XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retrovirus-mediated DNA repair gene transfer into xeroderma pigmentosum cells: perspectives for a gene therapy.PMID 9553721Read ↗

Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.Semantic proximity Read ↗

Functional retroviral vector for gene therapy of xeroderma pigmentosum group D patients.Semantic proximity Read ↗

Molecular genetics of Xeroderma pigmentosum variant.Semantic proximity Read ↗

Xeroderma pigmentosum--bridging a gap between clinic and laboratory.Semantic proximity Read ↗

Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus.Semantic proximity Read ↗

Isolation by polymerase chain reaction of a cDNA whose product partially complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells.Semantic proximity Read ↗

Stable transformation of xeroderma pigmentosum group A cells with an XPA minigene restores normal DNA repair and mutagenesis of UV-treated plasmids.Semantic proximity Read ↗

Mutation and expression of the XPA gene in revertants and hybrids of a xeroderma pigmentosum cell line.Semantic proximity Read ↗

Do we know the cause of xeroderma pigmentosum?Semantic proximity Read ↗

[Xeroderma pigmentosum (XP) : A genetic disease sheds light on UV-induced skin cancer].Semantic proximity Read ↗

[Xeroderma pigmentosum].Semantic proximity Read ↗

Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.