Article
Do we know the cause of xeroderma pigmentosum?
Carcinogenesis - 1 Jun 1990
Cleaver J E
Abstract excerpt
DNA repair in mammals consists of a large family of genes that encode a variety of mutually interacting gene products. These gene products coordinately locate and prepare damaged sites in chromatin for eventual excision and replacement and interact with transcriptionally active and replicating regions. Subsets of repair genes are represented by the complementation groups of xeroderma pigmentosum (XP), Cockayne...
Topics
- Animals
- Cell Line
- DNA Repair
- Gene Expression
- Genetic Complementation Test
- Humans
- Mutation
- Neoplasms
- Transfection
- Xeroderma Pigmentosum