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Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus.

Cancer gene therapy - 1 Apr 2005

Armelini Melissa Gava, Muotri Alysson Renato, Marchetto Maria Carolina Nasser, de Lima-Bessa Keronninn Moreno, Sarasin Alain, Menck Carlos Frederico Martins

Abstract excerpt

The nucleotide excision repair (NER) is one of the major human DNA repair pathways. Defects in one of the proteins that act in this system result in three distinct autosomal recessive syndromes: xeroderma pigmentosum (XP), Cockayne syndrome (CS) and trichothiodystrophy (TTD). TFIIH is a nine-protein complex essential for NER activity, initiation of RNA polymerase II transcription and with a possible role in cell...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15650764
DOI: 10.1038/sj.cgt.7700797

Genes

CS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus.PMID 15650764Read ↗

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