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Article

Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.

Human gene therapy - 10 Oct 2002

Muotri Alysson Renato, Marchetto Maria Carolina Nasser, Zerbini Luiz Fernando Celidonio, Libermann Towia A, Ventura Armando Morais, Sarasin Alain, Menck Carlos Frederico Martins

Abstract excerpt

Nucleotide excision repair (NER) is one of the most versatile DNA repair mechanisms, ensuring the proper functioning and trustworthy transmission of genetic information in all living cells. The phenotypic consequences caused by NER defects in humans are autosomal recessive diseases such as xeroderma pigmentosum (XP). This syndrome is the most sun-sensitive disorder leading to a high frequency of skin cancer. The...

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Source

Identifiers

PMID: 12396616
DOI: 10.1089/104303402760372936

Genes

XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.PMID 12396616Read ↗

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