Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the PTEN gene in human meningiomas

1 Feb 1998

Abstract excerpt

Previous observations demonstrated that the neurofibromatosis type 2 gene (NF2) plays an important role in the pathogenesis of the transitional, fibroblastic and malignant variants of human meningiomas. No specific genes have been associated with the pathogenesis of meningothelial meningiomas and with the progression to anaplastic meningiomas. However, allelic losses on chromosomal arms 1p, 10q and 14q have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroendocrine Tumor Research Advances
Share to Neurofibromatosis and Schwannoma Cases
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9549723
DOI: 10.1046/j.1365-2990.1998.00093.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the PTEN gene in human meningiomasPMID 9549723Read ↗

PTEN mutations in malignant gliomas and their relation with meningeal gliomatosis.Semantic proximity Read ↗

Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations.Semantic proximity Read ↗

Immunocytochemical mapping of the phosphatase and tensin homolog (PTEN/MMAC1) tumor suppressor protein in human gliomas.Semantic proximity Read ↗

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain.Semantic proximity Read ↗

Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation.Semantic proximity Read ↗

Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression.Semantic proximity Read ↗

Comparative analysis of the NF2, TP53, PTEN, KRAS, NRAS and HRAS genes in sporadic and radiation-induced human meningiomas.Semantic proximity Read ↗

Functional evaluation of p53 and PTEN gene mutations in gliomas.Semantic proximity Read ↗

Conditional Inactivation of<i>Pten</i>with<i>EGFR</i>Overexpression in Schwann Cells Models Sporadic MPNSTSemantic proximity Read ↗

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.Semantic proximity Read ↗

PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas.Semantic proximity Read ↗

Genetic profile, PTEN mutation and therapeutic role of PTEN in glioblastomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.