Article
Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations.
International journal of cancer - 20 Apr 1999
Zhou X P, Li Y J, Hoang-Xuan K, Laurent-Puig P, Mokhtari K, Longy M, Sanson M, Delattre J Y, Thomas G, Hamelin R
Abstract excerpt
The PTEN gene, recently identified on chromosome 10q23, has been proposed to be a candidate tumor suppressor gene inactivated in multiple cancers including glial tumors. We investigated 47 glioblastomas (GBM), 14 anaplastic astrocytomas (AA), 6 non-pilocytic low-grade astrocytomas (LGA), 21 low-g...
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