C4A and C4B null alleles are genetic markers of different types of systemic sclerosis in Japanese patients.

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Article

C4A and C4B null alleles are genetic markers of different types of systemic sclerosis in Japanese patients.

Clinical and experimental rheumatology - 1 Jan 2000

Takeuchi F, Nabeta H, Hong G H, Matsuta K, Tokunaga K, Tanimoto K, Nakano K

Abstract excerpt

OBJECTIVE: The contribution of the polymorphism of complement C4A and C4B alleles to the pathogenesis of systemic sclerosis (SSc) was studied in Japanese patients. METHODS: C4A and C4B typing was carried out in 44 SSc patients and in 83 normal subjects using electrophoresis followed by immunofixa...

Topics

Adult
Aged
Alleles
Complement C4a
Complement C4b
Female
Genetic Markers
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DRB1 Chains
Histocompatibility Testing
Humans
Japan
Male
Middle Aged
Phenotype
Polymorphism, Genetic
Scleroderma, Systemic

Source

Open in PubMed

Identifiers

PMID: 9543562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9543562-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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