Article
Relative contributions of HLA-DQA and complement C4A loci in determining susceptibility to systemic lupus erythematosus.
British journal of rheumatology - 1 Mar 1995
Davies E J, Steers G, Ollier W E, Grennan D M, Cooper R G, Hay E M, Hillarby M C
Abstract excerpt
The objective of this study was to reassess the role of C4A null alleles in systemic lupus erythematosus (SLE) susceptibility after taking into account the association of DQA*0501 with this disease. The frequency of C4A null alleles in 82 SLE patients and 59 controls was determined using both immunofixation and a TaqI RFLP method. HLA-DQA and DQB alleles were identified by sequence-specific oligonucleotide...
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