Article
Relative contributions of HLA-DQA and complement C4A loci in determining susceptibility to systemic lupus erythematosus.
British journal of rheumatology - 1 Mar 1995
Davies E J, Steers G, Ollier W E, Grennan D M, Cooper R G, Hay E M, Hillarby M C
Abstract excerpt
The objective of this study was to reassess the role of C4A null alleles in systemic lupus erythematosus (SLE) susceptibility after taking into account the association of DQA*0501 with this disease. The frequency of C4A null alleles in 82 SLE patients and 59 controls was determined using both imm...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Child
- Complement C4a
- Female
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Lupus Erythematosus, Systemic
