Article
A molecular and serologic analysis of the major histocompatibility complex and complement component C4 in systemic sclerosis.
Arthritis and rheumatism - 1 Jul 1993
Briggs D, Stephens C, Vaughan R, Welsh K, Black C
Abstract excerpt
OBJECTIVE: To investigate the contributions of the major histocompatibility complex (MHC) and C4 alleles to systemic sclerosis (SSc), and to pulmonary fibrosis and autoantibody expression in SSc, by analysis at the DNA level. METHODS: One hundred fifteen patients with SSc were tested serologicall...
Topics
- Alleles
- Autoantibodies
- Base Sequence
- Complement C4
- Female
- HLA-DQ Antigens
- HLA-DR Antigens
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Humans
- Major Histocompatibility Complex
- Male
- Molecular Sequence Data
- Pulmonary Fibrosis
- Scleroderma, Systemic