Association of the complement allele C4AQ0 with primary Sjögren's syndrome in Japanese patients.

doi:10.1002/art.1780340216

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Article

Association of the complement allele C4AQ0 with primary Sjögren's syndrome in Japanese patients.

Arthritis and rheumatism - 1 Feb 1991

Moriuchi J, Ichikawa Y, Takaya M, Shimizu H, Tsuji K, Wakisaka A, Dawkins R, Arimori S

Abstract excerpt

We studied allotypes of the fourth component of complement (C4) and factor B in 76 patients with Sjögren's syndrome (SS) and in 63 normal subjects. C4A-null (C4AQ0) was found in 10 of 28 patients who had primary SS, compared with 1 of 63 control subjects (P less than 0.005). In contrast, no signi...

Topics

Autoimmune Diseases
Complement C4
Complement Factor B
Humans
Immunoglobulin Allotypes
Japan
Phenotype
Sjogren's Syndrome

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