Article
Molecular heterogeneity of second and fourth components of complement and their genes in systemic sclerosis and association of HLA alleles A1, B8 and DR3 with limited and DR5 with diffuse systemic sclerosis.
Experimental and clinical immunogenetics - 1 Jan 1998
Venneker G T, van den Hoogen F H, van Meegen M, de Kok-Nazaruk M, Hulsmans R F, Boerbooms A M, de Waal L P, Bos J D, Asghar S S
Abstract excerpt
Deficiency of the complement component C4 at the functional, protein and gene level and deficiency of complement component C2 at the functional level were investigated and HLA analysis was performed on patients with limited and diffuse systemic sclerosis (SSc). One of the patients with limited SS...
Topics
- Alleles
- Case-Control Studies
- Complement C2
- Complement C4
- HLA Antigens
- HLA-A1 Antigen
- HLA-B8 Antigen
- HLA-DR3 Antigen
- HLA-DR5 Antigen
- Haplotypes
- Humans