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Article

Association of complement C4 and HLA-DR alleles with systemic lupus erythematosus in Koreans.

The Journal of rheumatology - 1 Mar 1994

Hong G H, Kim H Y, Takeuchi F, Nakano K, Yamada H, Matsuta K, Han H, Tokunaga K, Ito K, Park K S

Abstract excerpt

OBJECTIVE: To examine the association of complement C4 and HLA-DR to systemic lupus erythematosus (SLE) susceptibility in Korea. METHODS: Complement C4 protein typing was carried out by immunofixation and immunoblotting methods using EDTA-plasma from 60 patients with SLE and 72 healthy controls. Restriction fragment length polymorphism analysis of C4 genes was also carried out using TaqI or HindIII for...

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PMID: 7911834

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