Article
Association of complement C4 and HLA-DR alleles with systemic lupus erythematosus in Koreans.
The Journal of rheumatology - 1 Mar 1994
Hong G H, Kim H Y, Takeuchi F, Nakano K, Yamada H, Matsuta K, Han H, Tokunaga K, Ito K, Park K S
Abstract excerpt
OBJECTIVE: To examine the association of complement C4 and HLA-DR to systemic lupus erythematosus (SLE) susceptibility in Korea. METHODS: Complement C4 protein typing was carried out by immunofixation and immunoblotting methods using EDTA-plasma from 60 patients with SLE and 72 healthy controls. Restriction fragment length polymorphism analysis of C4 genes was also carried out using TaqI or HindIII for...
Topics
- Adult
- Aged
- Alleles
- Asian People
- Autoimmune Diseases
- Base Sequence
- Complement C4
- Disease Susceptibility
- Female
- Gene Deletion
- Gene Frequency
- Genetic Predisposition to Disease