Article
5HT2C CYS23/SER23 polymorphism is not associated with obsessive-compulsive disorder.
Psychiatry research - 9 Feb 1998
Cavallini M C, Di Bella D, Pasquale L, Henin M, Bellodi L
Abstract excerpt
A great deal of evidence suggests that a genetic component underlies obsessive-compulsive disorder (OCD). The response to serotonergic medications and the worsening of obsessive symptoms after administration of serotonergic agonists indicate that serotonergic mechanisms are involved in OCD. We investigated the role of the Cys23Ser mutation of the 5HT2C receptor gene in the etiology of this disorder by performing...
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