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Article

Association study between obsessive-compulsive disorder and serotonergic candidate genes.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Apr 2008

Saiz Pilar A, Garcia-Portilla Maria P, Arango Celso, Morales Blanca, Bascaran Maria-Teresa, Martinez-Barrondo Sara, Florez Gerardo, Sotomayor Emilio, Paredes Begoña, Alvarez Cesar, San Narciso Gema, Carreño Eduardo, Bombin Igor, Alvarez Victoria, Coto Eliecer, Fernandez Juan M, Bousoño Manuel, Bobes Julio

Abstract excerpt

BACKGROUND: To date, research examining the relationship between serotonergic genes and obsessive-compulsive disorder (OCD) has yielded conflicting results. The purpose of this study is to investigate the association between four serotonergic polymorphisms (STin2 VNTR and 5-HTTLPR of the SLC6A4 gene, and A-1438G (rs6311) and T102C (rs6313) of the HTR2A gene) and OCD. METHODS: 99 OCD patients, 456 non-OCD...

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Share to Chi-Square Distribution
Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Linkage Disequilibrium
Share to Obsessive-Compulsive Disorder
Share to Polymorphism, Genetic
Share to Receptor, Serotonin, 5-HT2A
Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 18191318
DOI: 10.1016/j.pnpbp.2007.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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