Article
5-HT2A promoter polymorphism -1438G/A in children and adolescents with obsessive-compulsive disorders.
Molecular psychiatry - 1 Jan 2002
Walitza S, Wewetzer C, Warnke A, Gerlach M, Geller F, Gerber G, Görg T, Herpertz-Dahlmann B, Schulz E, Remschmidt H, Hebebrand J, Hinney A
Abstract excerpt
Positive association between obsessive compulsive disorder (OCD) and the A-allele of the 5-HT(2A)-receptor promoter polymorphism -1438G/A has recently been reported in adults. We performed an association analysis of this polymorphism in 55 children and adolescents with OCD and in 223 controls consisting of unrelated students. We detected statistically significant differences in genotype (P < 0.05) and allele...
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