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Article

Efficacy and side-effects of clozapine not associated with variation in the 5-HT2C receptor.

Neuroreport - 27 May 1997

Rietschel M, Naber D, Fimmers R, Möller H J, Propping P, Nöthen M M

Abstract excerpt

In the present study we tested the hypothesis that individual response to clozapine treatment and/or the occurrence of side-effects may be influenced by genetic variation in the serotonin 5-HT2C receptor. We investigated the frequency of a common Cys23Ser substitution, which is known to alter the pharmacological properties of the protein, in 152 patients treated with clozapine. Presence of the Ser23 variant was...

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Identifiers

PMID: 9223092
DOI: 10.1097/00001756-199705260-00040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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