A high incidence of apolipoprotein E epsilon4 allele in middle-aged non-demented subjects with cerebral amyloid beta protein deposits.

doi:10.1007/s004010050958

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Article

A high incidence of apolipoprotein E epsilon4 allele in middle-aged non-demented subjects with cerebral amyloid beta protein deposits.

Acta neuropathologica - 1 Jan 1999

Arai T, Ikeda K, Akiyama H, Haga C, Usami M, Sahara N, Iritani S, Mori H

Abstract excerpt

We examined the apolipoprotein E (ApoE) genotypes of 19 middle-aged non-demented subjects with cerebral amyloid beta protein (Abeta) deposits, and compared the results with those of 16 patients with sporadic Alzheimer's disease (AD) and those of 34 age-matched controls. The frequency of the ApoE...

Topics

Adult
Alleles
Amyloid beta-Peptides
Apolipoprotein E4
Apolipoproteins E
Cerebral Cortex
Gene Frequency
Hippocampus
Humans
Middle Aged
Neurofibrillary Tangles
Plaque, Amyloid

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