Article
Trans-activation of the Tetrahymena ribozyme by its P2-2.1 domains.
Journal of biochemistry - 1 Mar 1998
Ikawa Y, Shiraishi H, Inoue T
Abstract excerpt
The Tetrahymena group I self-splicing intron contains peripheral domains P2-2.1. Mutant introns lacking these domains are hardly active. We found that if an independently prepared P2-2.1 RNA is added in trans, it efficiently enhances the catalytic activity of an intron lacking the domains. P2-2.1...
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