Article
The prognostic value of p53 immunostaining in node-negative breast carcinoma.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Sept 2007
Soontrapornchai Prinya, Chanvitan Apinop, Koontongkaew Sittichai, Sunpaweravong Somkiat
Abstract excerpt
BACKGROUND: P53 plays a key role in cell cycle arrest, apoptosis, DNA repair, and angiogenesis. Although some studies have reported as prognostic factor for poor survival in node-positive breast cancer, controversy about possible prognostic index for node-negative still exists. OBJECTIVES: To look for correlations between the expression of the p53 protein and clinicopathological parameters, and to assess its...
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