Article
p53 Status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: a novel hypothesis based on clinical findings.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 1995
Jansson T, Inganäs M, Sjögren S, Norberg T, Lindgren A, Holmberg L, Bergh J
Abstract excerpt
PURPOSE AND METHODS: Primary breast cancer tumors without axillary metastases from 206 consecutive patients in a population-based cohort were investigated with regard to the presence of an intact p53 gene using a cDNA-based sequencing method. Clinical follow-up data and outcome of node-negative p...
Topics
- Adult
- Aged
- Breast Neoplasms
- Cohort Studies
- Combined Modality Therapy
- DNA Mutational Analysis
- Disease-Free Survival
- Female
- Follow-Up Studies
- Genes, p53
- Humans
- Mastectomy
- Middle Aged
- Mutation
- Prognosis