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Article

Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.

Cancer research - 1 Apr 1998

Nomoto S, Haruki N, Kondo M, Konishi H, Takahashi T, Takahashi T, Takahashi T

Abstract excerpt

We examined 61 lung cancer cases to determine whether alterations of p73, a novel monoallelically expressed p53-like molecule, may be involved in the pathogenesis of lung cancer. Allelic loss at the p73 locus at 1p36.33 was observed in 42% (11 of 26 informative cases), and squamous cell carcinoma...

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Identifiers

PMID: 9537234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9537234-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.PMID 9537234Read ↗

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers.Semantic proximity Read ↗

p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas.Semantic proximity Read ↗

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.Semantic proximity Read ↗

Activation of p73 silent allele in lung cancer.Semantic proximity Read ↗

Genomic and allelic expression status of the p73 gene in human neuroblastoma.Semantic proximity Read ↗

Frequent inactivation of the <i>p73</i> gene by abnormal methylation or LOH in non‐Hodgkin's lymphomasSemantic proximity Read ↗

Clinical value of alterations in p73 gene, related to p53 at 1p36, in human hepatocellular carcinoma.Semantic proximity Read ↗

p73, a gene related to p53, is not mutated in esophageal carcinomas.Semantic proximity Read ↗

Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity.Semantic proximity Read ↗

Allelic loss at the p73 locus (1p36.33) is infrequent in malignant melanoma.Semantic proximity Read ↗

Infrequent somatic mutations of the p73 gene in various human cancers.Semantic proximity Read ↗

Mutational analysis of the p73 gene in human breast cancers.Semantic proximity Read ↗

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