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Article

Activation of p73 silent allele in lung cancer.

Cancer research - 1 Jun 1998

Mai M, Yokomizo A, Qian C, Yang P, Tindall D J, Smith D I, Liu W

Abstract excerpt

p73, a first p53 relative, has recently been identified and demonstrated to be monoallelically expressed. This protein shows significant amino acid sequence and functional similarities to p53. However, it is unclear whether this protein functions as a tumor suppressor. To elucidate the role of p7...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9622072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9622072-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Activation of p73 silent allele in lung cancer.PMID 9622072Read ↗

The expression of p73 is increased in lung cancer, independent of p53 gene alteration.Semantic proximity Read ↗

Mutational analysis of p73 and p53 in human cancer cell lines.Semantic proximity Read ↗

Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.Semantic proximity Read ↗

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Allelic expression and quantitative RT-PCR study of TAp73 and DeltaNp73 in non-Hodgkin's lymphomas.Semantic proximity Read ↗

Overexpression of the wild type p73 gene in breast cancer tissues and cell lines.Semantic proximity Read ↗

Allelic expression of the putative tumor suppressor gene p73 in human fetal tissues and tumor specimens.Semantic proximity Read ↗

A naturally occurring p73 mutation in a p73-p53 double-mutant lung cancer cell line encodes p73 alpha protein with a dominant-negative function.Semantic proximity Read ↗

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.Semantic proximity Read ↗

Loss of imprinting and elevated expression of wild-type p73 in human gastric adenocarcinoma.Semantic proximity Read ↗

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