Article
Angiotensin-converting enzyme gene polymorphism is associated with endothelium-dependent vasodilation in never treated hypertensive patients.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 1998
Perticone F, Ceravolo R, Maio R, Ventura G, Zingone A, Perrotti N, Mattioli P L
Abstract excerpt
The response of the forearm vasculature to acetylcholine (7.5, 15, and 30 microg/min, each for 5 minutes) and sodium nitroprusside (0.8, 1.6, and 3.2 microg/min, each for 5 minutes) was evaluated in 32 never-treated hypertensive outpatients (17 men and 15 women, aged 43+/-7 years) and in 24 normo...
Topics
- Adult
- Analysis of Variance
- Blood Pressure
- Endothelium, Vascular
- Female
- Genotype
- Humans
- Hypertension
- Male
- Middle Aged
- Multivariate Analysis
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Vasodilation