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Article

DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans.

Hypertension (Dallas, Tex. : 1979) - 1 May 1999

Butler R, Morris A D, Burchell B, Struthers A D

Abstract excerpt

A polymorphism within the angiotensin-converting enzyme (ACE) gene may increase the risk of myocardial infarction in individuals previously thought to be at low cardiovascular risk. The mechanism through which it exerts this effect is unknown but may be due to increased angiotensin II-induced nitric oxide (NO) breakdown and/or reduced bradykinin-mediated NO release. We investigated whether endothelial function...

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Source

Identifiers

PMID: 10334805
DOI: 10.1161/01.hyp.33.5.1164

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans.PMID 10334805Read ↗

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