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Article

Exclusion of the ACE D/I gene polymorphism as a determinant of endothelial dysfunction.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2001

Rossi G P, Taddei S, Virdis A, Ghiadoni L, Albertin G, Favilla S, Sudano I, Pessina A C, Salvetti A

Abstract excerpt

A deletion/insertion (D/I) polymorphism within the ACE gene may increase the risk of cardiovascular events through still unknown mechanisms. The latter may involve increased angiotensin II-induced NO breakdown and/or reduced agonist-mediated NO release. We therefore investigated whether the D allele of the ACE gene affects endothelium-dependent vasodilatation in mild-to-moderate primary hypertensive patients and...

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Source

Identifiers

PMID: 11230288
DOI: 10.1161/01.hyp.37.2.293

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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