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Article

Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors.

Atherosclerosis - 1 Nov 1994

Celermajer D S, Sorensen K E, Barley J, Jeffrey S, Carter N, Deanfield J

Abstract excerpt

The DD genotype is a polymorphism of the angiotensin-converting enzyme (ACE) gene, and is associated with a significantly increased risk of myocardial infarction. As endothelial dysfunction is an important event in both early atherogenesis and late atherosclerosis, we hypothesised that the advers...

Topics

Adolescent
Adult
Aged
Brachial Artery
Coronary Artery Disease
Endothelium, Vascular
Female
Forearm
Genotype
Humans
Hyperemia
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nitroglycerin

Peptidyl-Dipeptidase A

Risk Factors

Vasodilation

Source

Identifiers

PMID: 7840807
DOI: 10.1016/0021-9150(94)90197-x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7840807-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors.PMID 7840807Read ↗

DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans.Semantic proximity Read ↗

[Effect of angiotensin converting enzyme genotype on endothelial function in healthy subjects].Semantic proximity Read ↗

The ACE-DD genotype is associated with endothelial dysfunction in postmenopausal women.Semantic proximity Read ↗

Exclusion of the ACE D/I gene polymorphism as a determinant of endothelial dysfunction.Semantic proximity Read ↗

Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease.Semantic proximity Read ↗

ACE genotype and endothelium-dependent vasodilation of conduit arteries and forearm microcirculation in humans.Semantic proximity Read ↗

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