Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors.

Atherosclerosis - 1 Nov 1994

Celermajer D S, Sorensen K E, Barley J, Jeffrey S, Carter N, Deanfield J

Abstract excerpt

The DD genotype is a polymorphism of the angiotensin-converting enzyme (ACE) gene, and is associated with a significantly increased risk of myocardial infarction. As endothelial dysfunction is an important event in both early atherogenesis and late atherosclerosis, we hypothesised that the adverse effect associated with the ACE/DD genotype might be mediated via endothelial damage. Using high resolution...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to ACE gene

Share to Genotype

Share to Peptidyl-Dipeptidase A

Share to Risk Factors

Source

Identifiers

PMID: 7840807
DOI: 10.1016/0021-9150(94)90197-x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors.PMID 7840807Read ↗

DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans.Semantic proximity Read ↗

[Effect of angiotensin converting enzyme genotype on endothelial function in healthy subjects].Semantic proximity Read ↗

The ACE-DD genotype is associated with endothelial dysfunction in postmenopausal women.Semantic proximity Read ↗

Exclusion of the ACE D/I gene polymorphism as a determinant of endothelial dysfunction.Semantic proximity Read ↗

Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease.Semantic proximity Read ↗

ACE genotype and endothelium-dependent vasodilation of conduit arteries and forearm microcirculation in humans.Semantic proximity Read ↗

Angiotensin-converting enzyme gene polymorphism and coronary reactivity in young men.Semantic proximity Read ↗

Angiotensin-converting enzyme gene polymorphism is associated with endothelium-dependent vasodilation in never treated hypertensive patients.Semantic proximity Read ↗

Apolipoprotein e4 allele and endothelium-dependent arterial dilation in Type 2 diabetes mellitus without angiopathy.Semantic proximity Read ↗

Angiotensin converting enzyme gene polymorphism and carotid atherosclerosis in a low-risk population.Semantic proximity Read ↗

Lack of association between endothelial nitric oxide synthase gene polymorphisms, microalbuminuria and endothelial dysfunction in hypertensive men.Semantic proximity Read ↗

Association between angiotensin I-converting enzyme genotypes, extracranial artery stenosis, and stroke.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.