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Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility.

Biological psychiatry - 15 Mar 1998

Karayiorgou M, Gogos J A, Galke B L, Wolyniec P S, Nestadt G, Antonarakis S E, Kazazian H H, Housman D E, Pulver A E

Abstract excerpt

BACKGROUND: Deletions of 1.5-2 MB of chromosome 22q11 have been previously associated with schizophrenia. The deleted region includes proximally the region harboring genes involved in DiGeorge and velocardiofacial syndromes. Distally, it includes the gene for catechol-O-methyl-transferase (COMT),...

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Base Sequence
Exons
Genetic Variation
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 9532347
DOI: 10.1016/s0006-3223(97)00202-3

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9532347-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility.PMID 9532347Read ↗

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