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Article

Identification of a BglI polymorphism of catechol-O-methyltransferase (COMT) gene, and association study with schizophrenia.

American journal of medical genetics - 22 Nov 1996

Chen C H, Lee Y R, Liu M Y, Wei F C, Koong F J, Hwu H G, Hsiao K J

Abstract excerpt

Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-O-methyl-transferase (COMT), which is involved in the metabolism of catecholamines, was mapped to 22q11 and is considered a possible candidate gene for schizophrenia. Recently, we identi...

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Genotype
Polymerase Chain Reaction
Polymorphism, Genetic
Deoxyribonucleases, Type II Site-Specific
Schizophrenia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Catechol O-Methyltransferase

Source

Identifiers

PMID: 8950414
DOI: 10.1002/(SICI)1096-8628(19961122)67:6<556::AID-AJMG8>3.0.CO;2-F

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8950414-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Identification of a BglI polymorphism of catechol-O-methyltransferase (COMT) gene, and association study with schizophrenia.PMID 8950414Read ↗

No association of catechol-O-methyltransferase polymorphisms with schizophrenia in the Han Chinese population.Semantic proximity Read ↗

Systematic mutation analysis of the catechol O-methyltransferase gene as a candidate gene for schizophrenia.Semantic proximity Read ↗

No associations exist between five functional polymorphisms in the catechol-O-methyltransferase gene and schizophrenia in a Japanese population.Semantic proximity Read ↗

Association analysis of COMT polymorphisms and schizophrenia in a Chinese Han population: a case-control study.Semantic proximity Read ↗

Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics.Semantic proximity Read ↗

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample.Semantic proximity Read ↗

Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility.Semantic proximity Read ↗

Meta-analysis of association between genetic variants in COMT and schizophrenia: an update.Semantic proximity Read ↗

Functional catechol-O-methyltransferase gene polymorphism and susceptibility to schizophrenia.Semantic proximity Read ↗

[An association study of COMT gene polymorphisms with schizophrenia].Semantic proximity Read ↗

Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment.Semantic proximity Read ↗

Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia.Semantic proximity Read ↗

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