Article
Functional catechol-O-methyltransferase gene polymorphism and susceptibility to schizophrenia.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Aug 2002
Park Tae-Won, Yoon Kyung-Sik, Kim Ju-Han, Park Woong-Yang, Hirvonen Ari, Kang Daehee
Abstract excerpt
Genetic polymorphism of catechol-O-methyltransferase (COMT), involved in the degradation of catecholamine neurotransmitters, has been investigated as a candidate for modifier of susceptibility to development of schizophrenia. To address this issue further, we carried out a study in Korean schizophrenic patients and controls. The study population consisted of 103 Korean inpatients diagnosed as schizophrenic and...
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