Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis

doi:10.1152/ajpgi.1998.274.3.g544

Article

Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis

1 Mar 1998

Abstract excerpt

Dextran sulfate sodium (DSS)-induced murine colitis represents an experimental model for human inflammatory bowel disease. The aim of this study was to screen various inbred strains of mice for genetically determined differences in susceptibility to DSS-induced colitis. Mice of strains C3H/HeJ, C3H/HeJBir, C57BL/6J, DBA/2J, NOD/LtJ, NOD/LtSz-Prkdc(scid)/Prkdc(scid), 129/SvPas, NON/LtJ, and NON.NOD-H2g7 were fed...

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