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Article

Strain distribution pattern of susceptibility to immune-mediated nephritis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2004

Xie Chun, Sharma Ruchi, Wang Hongwei, Zhou Xin J, Mohan Chandra

Abstract excerpt

The genetic basis of immune-mediated nephritis is poorly understood. Recent studies have demonstrated that the NZW mouse strain is more prone to immune-mediated nephritis compared with C57BL/6 and BALB/c strains. The present study extends these findings by challenging 12 additional inbred strains of mice with rabbit anti-mouse glomerular basement membrane (GBM) reactive sera. Compared with control sera-injected...

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PMID: 15067087
DOI: 10.4049/jimmunol.172.8.5047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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