Article
Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice.
Gastroenterology - 1 Dec 1994
Sundberg J P, Elson C O, Bedigian H, Birkenmeier E H
Abstract excerpt
BACKGROUND/AIMS: C3H/HeJ mice at the Jackson Laboratory have periodically been culled because of the occurrence of soft feces, perianal ulceration, and right-sided colitis. No pathogens have been isolated. The goal of the current study was to establish a substrain with a high incidence of this disease. METHODS: Affected male and female C3H/HeJ mice were bred. The clinical, pathological, microbiological, and...
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