Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice.

doi:10.1016/0016-5085(94)90813-3

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Article

Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice.

Gastroenterology - 1 Dec 1994

Sundberg J P, Elson C O, Bedigian H, Birkenmeier E H

Abstract excerpt

BACKGROUND/AIMS: C3H/HeJ mice at the Jackson Laboratory have periodically been culled because of the occurrence of soft feces, perianal ulceration, and right-sided colitis. No pathogens have been isolated. The goal of the current study was to establish a substrain with a high incidence of this di...

Topics

Animals
Breeding
Cecum
Colitis
Colon
Disease Models, Animal
Female
Genetic Predisposition to Disease
Inflammatory Bowel Diseases
Male
Mice
Mice, Inbred C3H
Pedigree

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